Fabrication of biopolymer in situ-forming hydrogels

Jonathan Tersur Orasugh, Dipankar Chattopadhayay, Suprakas Sinha Ray, Anjan Adhikari

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

In situ-forming hydrogels have emerged as promising materials with diverse applications in the fields of drug delivery (DD), tissue engineering, and regenerative medicine. This chapter delves into the innovative realm of biopolymer-based in situ-forming hydrogels, offering a comprehensive overview of their design, engineering principles, and fabrication techniques. This chapter commences by elucidating the rationale behind selecting biopolymers as the fundamental constituents for these hydrogels. The inherent biocompatibility and versatility of biopolymers, such as alginate, chitosan, and hyaluronic acid, are discussed. Furthermore, various fabrication methods for biopolymer in situ-forming hydrogels are comprehensively covered. Techniques such as solution mixing, self-assembly, and in situ polymerization are discussed, highlighting their ability to create customized hydrogel structures and formats to meet the demands of specific applications. By consolidating the latest research and advancements in this field, this chapter serves as a valuable resource for researchers, scientists, and engineers involved in biomaterials, DD, and tissue engineering. The insights presented here not only expand our knowledge of these innovative materials but also pave the way for their continued development and application in the realm of biomedical sciences, ultimately contributing to enhanced healthcare solutions and improved patient care.

Original languageEnglish
Title of host publicationStimuli-Responsive Hydrogels for Ophthalmic Drug Delivery
PublisherElsevier
Pages239-265
Number of pages27
ISBN (Electronic)9780323991568
ISBN (Print)9780323993593
DOIs
Publication statusPublished - 1 Jan 2024

Keywords

  • Biopolymer
  • Drug delivery
  • Healthcare
  • In situ-forming hydrogels
  • Tissue engineering

ASJC Scopus subject areas

  • General Engineering
  • General Materials Science

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