Exploring the impact of ligand residence time on molecular communication system performance

Uche A.K. Chude-Okonkwo, B. T. Maharaj, Athanasios V. Vasilakos, Reza Malekian

Research output: Contribution to journalConference articlepeer-review

3 Citations (Scopus)


Information reception in artificially synthesized molecular communication (MC) systems ideally follows the mechanisms employed by natural nanosystems to communicate. One of such reception mechanism is the so called ligand-receptor binding. Contemporary research in MC has considerably discussed this mechanism; however, the impact of a crucial parameter associated with the ligand-receptor binding action has not been given appropriate attention in the MC literature. This parameter is termed the residence time, and has played very crucial role in defining for instance, the efficacy of drugs in therapeutic processes; hence, it is critical in the performance of MC. In this paper, we employ biophysical approach to model and discuss the influence of the ligand residence time on the performance of MC systems. The performance metrics considered here are the receiver sensitivity and the intersymbol interference. Numerical results that expose the impact of the residence time on these metrics, and the interrelationships between these metrics in MC system, are discussed.

Original languageEnglish
Article number9014054
JournalProceedings - IEEE Global Communications Conference, GLOBECOM
Publication statusPublished - 2019
Externally publishedYes
Event2019 IEEE Global Communications Conference, GLOBECOM 2019 - Waikoloa, United States
Duration: 9 Dec 201913 Dec 2019


  • Intersymbol interference
  • Molecular communication
  • Receiver sensitivity
  • Receptors
  • Residence time

ASJC Scopus subject areas

  • Artificial Intelligence
  • Computer Networks and Communications
  • Hardware and Architecture
  • Signal Processing


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