Exploring Anticancer Activity and DNA Binding of Metal (II) Salicylaldehyde Schiff Base Complexes: A Convergence of Experimental and Computational Perspectives

Keyphrases

• Anticancer Activity 100%
• DNA Binding 100%
• Metal(II) 100%
• Schiff Base Complexes 100%
• Salicylaldehyde 100%
• Salicylaldehyde Schiff Base 100%
• Computational Perspective 100%
• UV-VIS Spectroscopy 66%
• Schiff Base 66%
• Cancer Treatment 33%
• IC50 33%
• FTIR Analysis 33%
• Cytotoxicity 33%
• Doxorubicin 33%
• LDH Assay 33%
• MCF-7 Cells 33%
• Anticancer Effect 33%
• Benzonitrile 33%
• Metal Complexes 33%
• MTT Assay 33%
• Molecular Dynamics Simulation 33%
• Docking Dynamics 33%
• Characterization Techniques 33%
• MCF-7 Cancer Cells 33%
• Solid State 33%
• ATP Assay 33%
• Amino 33%
• Homoleptic 33%
• Metal Salts 33%
• High Stability 33%
• Ni(II) 33%
• 1H nuclear Magnetic Resonance (1H NMR) 33%
• LC-MS Analysis 33%
• Cu(II) 33%
• AT-rich 33%
• Mononuclear Complexes 33%
• Co(II) 33%
• In Silico 33%
• SEM-EDX 33%
• CuPd 33%
• 13C NMR Analysis 33%
• Inhibition Effect 33%
• Pd2+ Ion 33%
• Structural Geometry 33%
• Single Crystal X-ray Diffraction (SCXRD) 33%
• UV LD 33%
• Extra Precision 33%
• CHNS Analysis 33%
• XP Docking 33%

Chemistry

• Salicylaldehyde 100%
• Imine 100%
• DNA Binding 100%
• Spectroscopy 50%
• ATP 25%
• Benzonitrile 25%
• 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium Bromide 25%
• Deoxyribonucleic Acid 25%
• IC50 25%
• Fourier Transform Infrared Spectroscopy 25%
• X-Ray Diffraction 25%
• 13C NMR Spectroscopy 25%
• High Resolution Mass Spectrometry (HRMS) 25%
• 1H NMR Spectroscopy 25%
• Single Crystal X-Ray Diffraction 25%
• Doxorubicin 25%
• Molecular Dynamics Simulation 25%