Evaluation of P-bridged biaryl phosphine ligands in palladium-catalysed Suzuki-Miyaura cross-coupling reactions

Jairus L. Lamola; Paseka T. Moshapo; Cedric W. Holzapfel; Munaka Christopher Maumela

doi:10.1039/d1ra04947j

Evaluation of P-bridged biaryl phosphine ligands in palladium-catalysed Suzuki-Miyaura cross-coupling reactions

Jairus L. Lamola, Paseka T. Moshapo, Cedric W. Holzapfel, Munaka Christopher Maumela

Chemical Sciences

Research output: Contribution to journal › Article › peer-review

18 Citations (Scopus)

Abstract

A family of biaryl phosphacyclic ligands derived from phobane and phosphatrioxa-adamantane frameworks is described. The rigid biaryl phosphacycles are efficient for Suzuki-Miyaura cross-coupling of aryl bromides and chlorides. In particular, coupling reactions of the challenging sterically hindered and heterocyclic substrates were viable at room temperature.

Original language	English
Pages (from-to)	26883-26891
Number of pages	9
Journal	RSC Advances
Volume	11
Issue number	43
DOIs	https://doi.org/10.1039/d1ra04947j
Publication status	Published - 18 Jul 2021

ASJC Scopus subject areas

General Chemistry
General Chemical Engineering

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10.1039/d1ra04947j

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title = "Evaluation of P-bridged biaryl phosphine ligands in palladium-catalysed Suzuki-Miyaura cross-coupling reactions",

abstract = "A family of biaryl phosphacyclic ligands derived from phobane and phosphatrioxa-adamantane frameworks is described. The rigid biaryl phosphacycles are efficient for Suzuki-Miyaura cross-coupling of aryl bromides and chlorides. In particular, coupling reactions of the challenging sterically hindered and heterocyclic substrates were viable at room temperature.",

author = "Lamola, \{Jairus L.\} and Moshapo, \{Paseka T.\} and Holzapfel, \{Cedric W.\} and Maumela, \{Munaka Christopher\}",

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doi = "10.1039/d1ra04947j",

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T1 - Evaluation of P-bridged biaryl phosphine ligands in palladium-catalysed Suzuki-Miyaura cross-coupling reactions

AU - Lamola, Jairus L.

AU - Moshapo, Paseka T.

AU - Holzapfel, Cedric W.

AU - Maumela, Munaka Christopher

PY - 2021/7/18

Y1 - 2021/7/18

N2 - A family of biaryl phosphacyclic ligands derived from phobane and phosphatrioxa-adamantane frameworks is described. The rigid biaryl phosphacycles are efficient for Suzuki-Miyaura cross-coupling of aryl bromides and chlorides. In particular, coupling reactions of the challenging sterically hindered and heterocyclic substrates were viable at room temperature.

AB - A family of biaryl phosphacyclic ligands derived from phobane and phosphatrioxa-adamantane frameworks is described. The rigid biaryl phosphacycles are efficient for Suzuki-Miyaura cross-coupling of aryl bromides and chlorides. In particular, coupling reactions of the challenging sterically hindered and heterocyclic substrates were viable at room temperature.

UR - https://www.scopus.com/pages/publications/85112467140

U2 - 10.1039/d1ra04947j

DO - 10.1039/d1ra04947j

M3 - Article

AN - SCOPUS:85112467140

SN - 2046-2069

VL - 11

SP - 26883

EP - 26891

JO - RSC Advances

JF - RSC Advances

IS - 43

ER -

Evaluation of P-bridged biaryl phosphine ligands in palladium-catalysed Suzuki-Miyaura cross-coupling reactions

Abstract

ASJC Scopus subject areas

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