TY - JOUR
T1 - Encapsulation of Gold Nanorods with Porphyrins for the Potential Treatment of Cancer and Bacterial Diseases
T2 - A Critical Review
AU - Hlapisi, Nthabeleng
AU - Motaung, Tshwafo E.
AU - Linganiso, Linda Z.
AU - Oluwafemi, Oluwatobi S.
AU - Songca, Sandile P.
N1 - Publisher Copyright:
© 2019 Nthabeleng Hlapisi et al.
PY - 2019
Y1 - 2019
N2 - Cancer and bacterial diseases have been the most incidental diseases to date. According to the World Health Report 2018, at least every family is affected by cancer around the world. In 2012, 14.1 million people were affected by cancer, and that figure is bound to increase to 21.6 million in 2030. Medicine therefore sorts out ways of treatment using conventional methods which have been proven to have many side effects. Researchers developed photothermal and photodynamic methods to treat both cancer and bacterial diseases. These methods pose fewer effects on the biological systems but still no perfect method has been synthesized. The review serves to explore porphyrin and gold nanorods to be used in the treatment of cancer and bacterial diseases: porphyrins as photosensitizers and gold nanorods as delivery agents. In addition, the review delves into ways of incorporating photothermal and photodynamic therapy aimed at producing a less toxic, more efficacious, and specific compound for the treatment.
AB - Cancer and bacterial diseases have been the most incidental diseases to date. According to the World Health Report 2018, at least every family is affected by cancer around the world. In 2012, 14.1 million people were affected by cancer, and that figure is bound to increase to 21.6 million in 2030. Medicine therefore sorts out ways of treatment using conventional methods which have been proven to have many side effects. Researchers developed photothermal and photodynamic methods to treat both cancer and bacterial diseases. These methods pose fewer effects on the biological systems but still no perfect method has been synthesized. The review serves to explore porphyrin and gold nanorods to be used in the treatment of cancer and bacterial diseases: porphyrins as photosensitizers and gold nanorods as delivery agents. In addition, the review delves into ways of incorporating photothermal and photodynamic therapy aimed at producing a less toxic, more efficacious, and specific compound for the treatment.
UR - http://www.scopus.com/inward/record.url?scp=85066074864&partnerID=8YFLogxK
U2 - 10.1155/2019/7147128
DO - 10.1155/2019/7147128
M3 - Review article
AN - SCOPUS:85066074864
SN - 1565-3633
VL - 2019
JO - Bioinorganic Chemistry and Applications
JF - Bioinorganic Chemistry and Applications
M1 - 7147128
ER -
