Electrospun PCL-Based Materials for Health-Care Applications: An Overview

Teboho Clement Mokhena; Mandla Brian Chabalala; Sivuyisiwe Mapukata; Asanda Mtibe; Lerato Hlekelele; Zamani Cele; Mokgaotsa Jonas Mochane; Bulelwa Ntsendwana; Toitoi Amos Nhlapo; Teboho Patrick Mokoena; Mokae Fanuel Bambo; Kgabo Phillemon Matabola; Suprakas Sinha Ray; Emmanuel Rotimi Sadiku; Katekani Shingange

doi:10.1002/mame.202300388

Electrospun PCL-Based Materials for Health-Care Applications: An Overview

Teboho Clement Mokhena, Mandla Brian Chabalala, Sivuyisiwe Mapukata, Asanda Mtibe, Lerato Hlekelele, Zamani Cele, Mokgaotsa Jonas Mochane, Bulelwa Ntsendwana, Toitoi Amos Nhlapo, Teboho Patrick Mokoena, Mokae Fanuel Bambo, Kgabo Phillemon Matabola, Suprakas Sinha Ray, Emmanuel Rotimi Sadiku, Katekani Shingange

Research output: Contribution to journal › Review article › peer-review

4 Citations (Scopus)

Abstract

Polycaprolactone (PCL) is one of the durable polymers with potential in a plethora of healthcare applications. Its biological properties, degradability, chemical properties, and mechanical properties can further be modified to manufacture desired products for modern biomedical applications. Electrospinning of PCL offers the opportunity to design treatment materials that resemble human tissues and facilitate regeneration at the target site. The resultant materials can also be modified by loading other active functional materials to broaden their applications. Herein, the recent advances in the preparation and modification of PCL-based materials for healthcare applications are elucidated. The challenges and future trends for its application in modern biomedical applications are also outlined.

Original language	English
Article number	2300388
Journal	Macromolecular Materials and Engineering
Volume	309
Issue number	8
DOIs	https://doi.org/10.1002/mame.202300388
Publication status	Published - Aug 2024
Externally published	Yes

Keywords

biomedical applications
blends
composites
polycaprolactone

ASJC Scopus subject areas

General Chemical Engineering
Polymers and Plastics
Organic Chemistry
Materials Chemistry

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10.1002/mame.202300388

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Mokhena, T. C., Chabalala, M. B., Mapukata, S., Mtibe, A., Hlekelele, L., Cele, Z., Mochane, M. J., Ntsendwana, B., Nhlapo, T. A., Mokoena, T. P., Bambo, M. F., Matabola, K. P., Ray, S. S., Sadiku, E. R., & Shingange, K. (2024). Electrospun PCL-Based Materials for Health-Care Applications: An Overview. Macromolecular Materials and Engineering, 309(8), Article 2300388. https://doi.org/10.1002/mame.202300388

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title = "Electrospun PCL-Based Materials for Health-Care Applications: An Overview",

abstract = "Polycaprolactone (PCL) is one of the durable polymers with potential in a plethora of healthcare applications. Its biological properties, degradability, chemical properties, and mechanical properties can further be modified to manufacture desired products for modern biomedical applications. Electrospinning of PCL offers the opportunity to design treatment materials that resemble human tissues and facilitate regeneration at the target site. The resultant materials can also be modified by loading other active functional materials to broaden their applications. Herein, the recent advances in the preparation and modification of PCL-based materials for healthcare applications are elucidated. The challenges and future trends for its application in modern biomedical applications are also outlined.",

keywords = "biomedical applications, blends, composites, polycaprolactone",

author = "Mokhena, {Teboho Clement} and Chabalala, {Mandla Brian} and Sivuyisiwe Mapukata and Asanda Mtibe and Lerato Hlekelele and Zamani Cele and Mochane, {Mokgaotsa Jonas} and Bulelwa Ntsendwana and Nhlapo, {Toitoi Amos} and Mokoena, {Teboho Patrick} and Bambo, {Mokae Fanuel} and Matabola, {Kgabo Phillemon} and Ray, {Suprakas Sinha} and Sadiku, {Emmanuel Rotimi} and Katekani Shingange",

note = "Publisher Copyright: {\textcopyright} 2024 The Authors. Macromolecular Materials and Engineering published by Wiley-VCH GmbH.",

year = "2024",

month = aug,

doi = "10.1002/mame.202300388",

language = "English",

volume = "309",

journal = "Macromolecular Materials and Engineering",

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Mokhena, TC, Chabalala, MB, Mapukata, S, Mtibe, A, Hlekelele, L, Cele, Z, Mochane, MJ, Ntsendwana, B, Nhlapo, TA, Mokoena, TP, Bambo, MF, Matabola, KP, Ray, SS, Sadiku, ER & Shingange, K 2024, 'Electrospun PCL-Based Materials for Health-Care Applications: An Overview', Macromolecular Materials and Engineering, vol. 309, no. 8, 2300388. https://doi.org/10.1002/mame.202300388

TY - JOUR

T1 - Electrospun PCL-Based Materials for Health-Care Applications

T2 - An Overview

AU - Mokhena, Teboho Clement

AU - Chabalala, Mandla Brian

AU - Mapukata, Sivuyisiwe

AU - Mtibe, Asanda

AU - Hlekelele, Lerato

AU - Cele, Zamani

AU - Mochane, Mokgaotsa Jonas

AU - Ntsendwana, Bulelwa

AU - Nhlapo, Toitoi Amos

AU - Mokoena, Teboho Patrick

AU - Bambo, Mokae Fanuel

AU - Matabola, Kgabo Phillemon

AU - Ray, Suprakas Sinha

AU - Sadiku, Emmanuel Rotimi

AU - Shingange, Katekani

PY - 2024/8

Y1 - 2024/8

N2 - Polycaprolactone (PCL) is one of the durable polymers with potential in a plethora of healthcare applications. Its biological properties, degradability, chemical properties, and mechanical properties can further be modified to manufacture desired products for modern biomedical applications. Electrospinning of PCL offers the opportunity to design treatment materials that resemble human tissues and facilitate regeneration at the target site. The resultant materials can also be modified by loading other active functional materials to broaden their applications. Herein, the recent advances in the preparation and modification of PCL-based materials for healthcare applications are elucidated. The challenges and future trends for its application in modern biomedical applications are also outlined.

AB - Polycaprolactone (PCL) is one of the durable polymers with potential in a plethora of healthcare applications. Its biological properties, degradability, chemical properties, and mechanical properties can further be modified to manufacture desired products for modern biomedical applications. Electrospinning of PCL offers the opportunity to design treatment materials that resemble human tissues and facilitate regeneration at the target site. The resultant materials can also be modified by loading other active functional materials to broaden their applications. Herein, the recent advances in the preparation and modification of PCL-based materials for healthcare applications are elucidated. The challenges and future trends for its application in modern biomedical applications are also outlined.

KW - biomedical applications

KW - blends

KW - composites

KW - polycaprolactone

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DO - 10.1002/mame.202300388

M3 - Review article

AN - SCOPUS:85187503826

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VL - 309

JO - Macromolecular Materials and Engineering

JF - Macromolecular Materials and Engineering

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ER -

Electrospun PCL-Based Materials for Health-Care Applications: An Overview

Abstract

Keywords

ASJC Scopus subject areas

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