TY - JOUR
T1 - Electroconductive multi-functional polypyrrole composites for biomedical applications
AU - Zare, Ehsan Nazarzadeh
AU - Agarwal, Tarun
AU - Zarepour, Atefeh
AU - Pinelli, Filippo
AU - Zarrabi, Ali
AU - Rossi, Filippo
AU - Ashrafizadeh, Milad
AU - Maleki, Aziz
AU - Shahbazi, Mohammad Ali
AU - Maiti, Tapas Kumar
AU - Varma, Rajender S.
AU - Tay, Franklin R.
AU - Hamblin, Michael R.
AU - Mattoli, Virgilio
AU - Makvandi, Pooyan
N1 - Publisher Copyright:
© 2021 Elsevier Ltd
PY - 2021/9
Y1 - 2021/9
N2 - Polypyrrole is an example of inherently electrically conductive polymer that is employed in the biomedical arena because of its low cost, excellent electroconductive properties, and good biocompatibility. Because many body tissues respond to electrical fields, polypyrrole-based nanocomposites have become an important class of bio-conductive material. Nanocomposites prepared by blending polypyrrole with other biopolymers or nanomaterials show marked improvements in physicochemical, mechanical, and biological properties. The present review outlines the structure and synthesis of polypyrrole, as well as the physical and mechanical properties of polypyrrole-containing nanocomposites. The antimicrobial and antioxidant activities and possible cytotoxicity of these nanocomposites are summarized and critiqued. A survey of the biomedical applications of polypyrrole as biosensors, drug delivery systems, tissue engineering scaffolds, or photo-thermal therapeutic agents is presented to spur further advances in this exciting field of research.
AB - Polypyrrole is an example of inherently electrically conductive polymer that is employed in the biomedical arena because of its low cost, excellent electroconductive properties, and good biocompatibility. Because many body tissues respond to electrical fields, polypyrrole-based nanocomposites have become an important class of bio-conductive material. Nanocomposites prepared by blending polypyrrole with other biopolymers or nanomaterials show marked improvements in physicochemical, mechanical, and biological properties. The present review outlines the structure and synthesis of polypyrrole, as well as the physical and mechanical properties of polypyrrole-containing nanocomposites. The antimicrobial and antioxidant activities and possible cytotoxicity of these nanocomposites are summarized and critiqued. A survey of the biomedical applications of polypyrrole as biosensors, drug delivery systems, tissue engineering scaffolds, or photo-thermal therapeutic agents is presented to spur further advances in this exciting field of research.
KW - Biomedical applications
KW - Inherently conductive polymer
KW - Nanocomposite
KW - Polypyrrole
KW - Tissue regeneration
UR - http://www.scopus.com/inward/record.url?scp=85110414868&partnerID=8YFLogxK
U2 - 10.1016/j.apmt.2021.101117
DO - 10.1016/j.apmt.2021.101117
M3 - Review article
AN - SCOPUS:85110414868
SN - 2352-9407
VL - 24
JO - Applied Materials Today
JF - Applied Materials Today
M1 - 101117
ER -