Effects of infant sex on mother-to-child transmission of HIV-1 according to timing of infection in Zimbabwe

Ellen G. Piwoz; Jean H. Humphrey; Edmore T. Marinda; Kuda Mutasa; Lawrence H. Moulton; Peter J. Iliff

doi:10.1097/01.aids.0000247123.04703.6e

Effects of infant sex on mother-to-child transmission of HIV-1 according to timing of infection in Zimbabwe

Ellen G. Piwoz
, Jean H. Humphrey
, Edmore T. Marinda
, Kuda Mutasa
, Lawrence H. Moulton
, Peter J. Iliff

FHI 360
Johns Hopkins University
ZVITAMBO Project
University of the Witwatersrand

Research output: Contribution to journal › Article › peer-review

12 Citations (Scopus)

Abstract

We examined the relationship between sex and the risk of intrauterine, intrapartum and postnatal HIV transmission among 4495 infants born to HIV-infected mothers in Harare, Zimbabwe. Intrauterine transmission was 8.6%, and consistent with other studies was higher among girl than boy infants (AOR 1.53; 95% CI 1.23-1.91). Unlike previous studies, we observed no independent effect of infant sex on intrapartum or breastfeeding-associated HIV transmission. Sex-specific postnatal prevention strategies are not warranted in this population.

Original language	English
Pages (from-to)	1981-1984
Number of pages	4
Journal	AIDS
Volume	20
Issue number	15
DOIs	https://doi.org/10.1097/01.aids.0000247123.04703.6e
Publication status	Published - Oct 2006
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being
SDG 5 Gender Equality

ASJC Scopus subject areas

Immunology and Allergy
Immunology
Infectious Diseases

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10.1097/01.aids.0000247123.04703.6e

Cite this

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title = "Effects of infant sex on mother-to-child transmission of HIV-1 according to timing of infection in Zimbabwe",

abstract = "We examined the relationship between sex and the risk of intrauterine, intrapartum and postnatal HIV transmission among 4495 infants born to HIV-infected mothers in Harare, Zimbabwe. Intrauterine transmission was 8.6\%, and consistent with other studies was higher among girl than boy infants (AOR 1.53; 95\% CI 1.23-1.91). Unlike previous studies, we observed no independent effect of infant sex on intrapartum or breastfeeding-associated HIV transmission. Sex-specific postnatal prevention strategies are not warranted in this population.",

author = "Piwoz, \{Ellen G.\} and Humphrey, \{Jean H.\} and Marinda, \{Edmore T.\} and Kuda Mutasa and Moulton, \{Lawrence H.\} and Iliff, \{Peter J.\}",

year = "2006",

month = oct,

doi = "10.1097/01.aids.0000247123.04703.6e",

language = "English",

volume = "20",

pages = "1981--1984",

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TY - JOUR

T1 - Effects of infant sex on mother-to-child transmission of HIV-1 according to timing of infection in Zimbabwe

AU - Piwoz, Ellen G.

AU - Humphrey, Jean H.

AU - Marinda, Edmore T.

AU - Mutasa, Kuda

AU - Moulton, Lawrence H.

AU - Iliff, Peter J.

PY - 2006/10

Y1 - 2006/10

N2 - We examined the relationship between sex and the risk of intrauterine, intrapartum and postnatal HIV transmission among 4495 infants born to HIV-infected mothers in Harare, Zimbabwe. Intrauterine transmission was 8.6%, and consistent with other studies was higher among girl than boy infants (AOR 1.53; 95% CI 1.23-1.91). Unlike previous studies, we observed no independent effect of infant sex on intrapartum or breastfeeding-associated HIV transmission. Sex-specific postnatal prevention strategies are not warranted in this population.

AB - We examined the relationship between sex and the risk of intrauterine, intrapartum and postnatal HIV transmission among 4495 infants born to HIV-infected mothers in Harare, Zimbabwe. Intrauterine transmission was 8.6%, and consistent with other studies was higher among girl than boy infants (AOR 1.53; 95% CI 1.23-1.91). Unlike previous studies, we observed no independent effect of infant sex on intrapartum or breastfeeding-associated HIV transmission. Sex-specific postnatal prevention strategies are not warranted in this population.

UR - https://www.scopus.com/pages/publications/33748910043

U2 - 10.1097/01.aids.0000247123.04703.6e

DO - 10.1097/01.aids.0000247123.04703.6e

M3 - Article

C2 - 16988523

AN - SCOPUS:33748910043

SN - 0269-9370

VL - 20

SP - 1981

EP - 1984

JO - AIDS

JF - AIDS

IS - 15

ER -

Effects of infant sex on mother-to-child transmission of HIV-1 according to timing of infection in Zimbabwe

Abstract

UN SDGs

ASJC Scopus subject areas

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