@inproceedings{4b41b14f06d94926916ca1b8b2affd64,
title = "Effectively simultaneous localized manipulation of multiple magnetic beads",
abstract = "The ability to simultaneously manipulate multiple magnetic particle (or beads) opens up new opportunities in conducting large-scale studies involving multiple biological objects. In this paper we present the development of two control schemes, namely PI control with an arbitrary control sequence and optimal control with a selected control sequence, for simultaneous position-regulation of magnetic beads under disturbances. A set of simulation studies were conducted in COMSOL to examine the effectiveness of the PI control, while a numerical simulation was carried out in MATLAB to demonstrate the feasibility of the proposed optimal control in dealing with a more complex situation that was modeled as a switched LQR problem. Particle Tracing Module for COMSOL was implemented to model the bead-fluid interaction during simulations. The results show the feasibility of both schemes in coordinated regulation of bead positions.",
keywords = "Magnetic beads, Micromanipulation, Optimal control, Simultaneous control",
author = "Yue Du and See, {Hian Hian} and Wang, {Qing Guo} and Chen, {Peter C.Y.}",
note = "Publisher Copyright: {\textcopyright} 2016 IEEE.; 2016 IEEE International Conference on Information and Automation, IEEE ICIA 2016 ; Conference date: 01-08-2016 Through 03-08-2016",
year = "2017",
month = jan,
day = "24",
doi = "10.1109/ICInfA.2016.7831801",
language = "English",
series = "2016 IEEE International Conference on Information and Automation, IEEE ICIA 2016",
publisher = "Institute of Electrical and Electronics Engineers Inc.",
pages = "85--90",
booktitle = "2016 IEEE International Conference on Information and Automation, IEEE ICIA 2016",
address = "United States",
}