Abstract
Diabetes is known to be associated with impaired wound healing, and loss of collagen related to diabetes may be due to decreased levels of synthesis or enhanced metabolism of newly synthesized collagen or both. This study aims to determine if laser irradiation stimulates cellular proliferation, nitric oxide (NO) and collagen synthesis in diabetic fibroblast cells. Induced diabetic wounded human fibroblast cells were irradiated at 830 nm with 5 J/cm 2. Post-laser irradiation there was a significant increase in proliferation at 24 and 48 h and reactive oxygen species and NO generation at 15 min. There was no change in collagen type I. Laser irradiation at 830 nm with 5 J/cm2 significantly stimulates cellular proliferation and NO synthesis in diabetic wounded fibroblast cells.
| Original language | English |
|---|---|
| Title of host publication | Proceedings of the International Conference of the World Association of Laser Therapy, WALT 2008 |
| Publisher | MEDIMOND s.r.l. |
| Pages | 29-35 |
| Number of pages | 7 |
| ISBN (Print) | 9788875874704 |
| Publication status | Published - 2008 |
| Event | 7th International Congress of the World Association of Laser Therapy, WALT 2008 - Sun City, North West Province, South Africa Duration: 19 Oct 2008 → 22 Oct 2008 |
Publication series
| Name | Proceedings of the International Conference of the World Association of Laser Therapy, WALT 2008 |
|---|
Conference
| Conference | 7th International Congress of the World Association of Laser Therapy, WALT 2008 |
|---|---|
| Country/Territory | South Africa |
| City | Sun City, North West Province |
| Period | 19/10/08 → 22/10/08 |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
ASJC Scopus subject areas
- Radiology, Nuclear Medicine and Imaging
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