Effect of laser irradiation on diabetic wounded fibroblast cells in vitro

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1 Citation (Scopus)

Abstract

Diabetes is known to be associated with impaired wound healing, and loss of collagen related to diabetes may be due to decreased levels of synthesis or enhanced metabolism of newly synthesized collagen or both. This study aims to determine if laser irradiation stimulates cellular proliferation, nitric oxide (NO) and collagen synthesis in diabetic fibroblast cells. Induced diabetic wounded human fibroblast cells were irradiated at 830 nm with 5 J/cm 2. Post-laser irradiation there was a significant increase in proliferation at 24 and 48 h and reactive oxygen species and NO generation at 15 min. There was no change in collagen type I. Laser irradiation at 830 nm with 5 J/cm2 significantly stimulates cellular proliferation and NO synthesis in diabetic wounded fibroblast cells.

Original languageEnglish
Title of host publicationProceedings of the International Conference of the World Association of Laser Therapy, WALT 2008
PublisherMEDIMOND s.r.l.
Pages29-35
Number of pages7
ISBN (Print)9788875874704
Publication statusPublished - 2008
Event7th International Congress of the World Association of Laser Therapy, WALT 2008 - Sun City, North West Province, South Africa
Duration: 19 Oct 200822 Oct 2008

Publication series

NameProceedings of the International Conference of the World Association of Laser Therapy, WALT 2008

Conference

Conference7th International Congress of the World Association of Laser Therapy, WALT 2008
Country/TerritorySouth Africa
CitySun City, North West Province
Period19/10/0822/10/08

ASJC Scopus subject areas

  • Radiology, Nuclear Medicine and Imaging

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