Easy Access to Phosphine-Borane Building Blocks

G. Bas de Jong, Nuria Ortega, Martin Lutz, Koop Lammertsma, J. Chris Slootweg

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)


In this paper, we highlight the synthesis of a variety of primary phosphine-boranes (RPH2⋅BH3) from the corresponding dichlorophosphines, simply by using Li[BH4] as reductant and provider of the BH3 protecting group. The method offers facile access not only to alkyl- and arylphosphine-boranes, but also to aminophosphine-boranes (R2NPH2⋅BH3) that are convenient building blocks but without the protecting BH3 moiety thermally labile and notoriously difficult to handle. The borane-protected primary phosphines can be doubly deprotonated using n-butyllithium to provide soluble phosphanediides Li2[RP⋅BH3] of which the phenyl-derivative Li2[PhP⋅BH3] was structurally characterized in the solid state.

Original languageEnglish
Pages (from-to)15944-15952
Number of pages9
JournalChemistry - A European Journal
Issue number68
Publication statusPublished - 4 Dec 2020


  • crystal structures
  • phosphanediide
  • phosphine borane
  • primary phosphine
  • synthesis

ASJC Scopus subject areas

  • Catalysis
  • Organic Chemistry


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