Abstract
The present work involves the development of curcumin loaded silver hydrogel nanocomposites based on acrylamide and 2-acrylamido-2-methyl propanesulfonic acid, as a template by redox co-polymerization in the presence of hydrophilic crosslinker N,N 1-methylenebisacrylamide. Silver nitrate was taken as the metal precursor and sodium borohydride as a reducing agent. The formation of silver nanoparticles was monitored using UV-Vis absorption spectroscopy. The developed hydrogel silver nanocomposites (HSNC) were characterized by FTIR, UV-Vis, thermogravimetric analysis, scanning electron microscopy and transmission electron microscopy. The curcumin loading and release characteristics were performed for different hydrogel systems. The developed HSNCs were evaluated for preliminary antibacterial applications.
| Original language | English |
|---|---|
| Pages (from-to) | 1254-1262 |
| Number of pages | 9 |
| Journal | Journal of Inorganic and Organometallic Polymers and Materials |
| Volume | 22 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - Nov 2012 |
Keywords
- Antibacterial activity
- Hydrogel network
- Silver nanoparticles
ASJC Scopus subject areas
- Polymers and Plastics
- Materials Chemistry
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