Designing biaryl phosphacyclic ligands: their characterization and evaluation in palladium-catalyzed Suzuki-Miyaura reactions of aryl bromides and chlorides

Jairus L. Lamola; Paseka T. Moshapo; Cedric W. Holzapfel; Munaka Christopher Maumela

doi:10.1080/10426507.2021.2012178

Designing biaryl phosphacyclic ligands: their characterization and evaluation in palladium-catalyzed Suzuki-Miyaura reactions of aryl bromides and chlorides

Jairus L. Lamola
, Paseka T. Moshapo
, Cedric W. Holzapfel
, Munaka Christopher Maumela

Chemical Sciences

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

Efficient palladium catalyst systems based on the combination of bench stable biaryl phosphacycles and Pd(OAc)₂ are described for Suzuki-Miyaura cross-coupling reactions of aryl bromides and chlorides. Notably, the electronically and sterically diametric biaryl phosphacycles allowed facile coupling of sterically hindered and heterocyclic substrates.

Original language	English
Pages (from-to)	587-592
Number of pages	6
Journal	Phosphorus, Sulfur and Silicon and the Related Elements
Volume	197
Issue number	5-6
DOIs	https://doi.org/10.1080/10426507.2021.2012178
Publication status	Published - 2022

Keywords

Biaryl phosphacycles
cross-coupling
electronic
steric
Suzuki-Miyaura

ASJC Scopus subject areas

Biochemistry
Organic Chemistry
Inorganic Chemistry

Access to Document

10.1080/10426507.2021.2012178

Cite this

@article{91765ed199dc4f0b86fcdb6a82bed12e,

title = "Designing biaryl phosphacyclic ligands: their characterization and evaluation in palladium-catalyzed Suzuki-Miyaura reactions of aryl bromides and chlorides",

abstract = "Efficient palladium catalyst systems based on the combination of bench stable biaryl phosphacycles and Pd(OAc)2 are described for Suzuki-Miyaura cross-coupling reactions of aryl bromides and chlorides. Notably, the electronically and sterically diametric biaryl phosphacycles allowed facile coupling of sterically hindered and heterocyclic substrates.",

keywords = "Biaryl phosphacycles, cross-coupling, electronic, steric, Suzuki-Miyaura",

author = "Lamola, \{Jairus L.\} and Moshapo, \{Paseka T.\} and Holzapfel, \{Cedric W.\} and Maumela, \{Munaka Christopher\}",

note = "Publisher Copyright: {\textcopyright} 2021 Taylor \& Francis Group, LLC.",

year = "2022",

doi = "10.1080/10426507.2021.2012178",

language = "English",

volume = "197",

pages = "587--592",

journal = "Phosphorus, Sulfur and Silicon and the Related Elements",

issn = "1042-6507",

publisher = "Taylor and Francis Ltd.",

number = "5-6",

}

Designing biaryl phosphacyclic ligands: their characterization and evaluation in palladium-catalyzed Suzuki-Miyaura reactions of aryl bromides and chlorides. / Lamola, Jairus L.; Moshapo, Paseka T.; Holzapfel, Cedric W. et al.
In: Phosphorus, Sulfur and Silicon and the Related Elements, Vol. 197, No. 5-6, 2022, p. 587-592.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Designing biaryl phosphacyclic ligands

T2 - their characterization and evaluation in palladium-catalyzed Suzuki-Miyaura reactions of aryl bromides and chlorides

AU - Lamola, Jairus L.

AU - Moshapo, Paseka T.

AU - Holzapfel, Cedric W.

AU - Maumela, Munaka Christopher

PY - 2022

Y1 - 2022

N2 - Efficient palladium catalyst systems based on the combination of bench stable biaryl phosphacycles and Pd(OAc)2 are described for Suzuki-Miyaura cross-coupling reactions of aryl bromides and chlorides. Notably, the electronically and sterically diametric biaryl phosphacycles allowed facile coupling of sterically hindered and heterocyclic substrates.

AB - Efficient palladium catalyst systems based on the combination of bench stable biaryl phosphacycles and Pd(OAc)2 are described for Suzuki-Miyaura cross-coupling reactions of aryl bromides and chlorides. Notably, the electronically and sterically diametric biaryl phosphacycles allowed facile coupling of sterically hindered and heterocyclic substrates.

KW - Biaryl phosphacycles

KW - cross-coupling

KW - electronic

KW - steric

KW - Suzuki-Miyaura

UR - https://www.scopus.com/pages/publications/85121372612

U2 - 10.1080/10426507.2021.2012178

DO - 10.1080/10426507.2021.2012178

M3 - Article

AN - SCOPUS:85121372612

SN - 1042-6507

VL - 197

SP - 587

EP - 592

JO - Phosphorus, Sulfur and Silicon and the Related Elements

JF - Phosphorus, Sulfur and Silicon and the Related Elements

IS - 5-6

ER -

Designing biaryl phosphacyclic ligands: their characterization and evaluation in palladium-catalyzed Suzuki-Miyaura reactions of aryl bromides and chlorides

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this