Designing biaryl phosphacyclic ligands: their characterization and evaluation in palladium-catalyzed Suzuki-Miyaura reactions of aryl bromides and chlorides

Jairus L. Lamola, Paseka T. Moshapo, Cedric W. Holzapfel, Munaka Christopher Maumela

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

Efficient palladium catalyst systems based on the combination of bench stable biaryl phosphacycles and Pd(OAc)2 are described for Suzuki-Miyaura cross-coupling reactions of aryl bromides and chlorides. Notably, the electronically and sterically diametric biaryl phosphacycles allowed facile coupling of sterically hindered and heterocyclic substrates.

Original languageEnglish
Pages (from-to)587-592
Number of pages6
JournalPhosphorus, Sulfur and Silicon and the Related Elements
Volume197
Issue number5-6
DOIs
Publication statusPublished - 2022

Keywords

  • Biaryl phosphacycles
  • cross-coupling
  • electronic
  • steric
  • Suzuki-Miyaura

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Inorganic Chemistry

Fingerprint

Dive into the research topics of 'Designing biaryl phosphacyclic ligands: their characterization and evaluation in palladium-catalyzed Suzuki-Miyaura reactions of aryl bromides and chlorides'. Together they form a unique fingerprint.

Cite this