Design and analysis of microfluidic channel with W-shaped electrodes for separation of bio-particles using dielectrophoresis technique

Muktimani Brahma, R. Kumar, Trigunesh Narzary

Research output: Contribution to journalArticlepeer-review

Abstract

A unique microfluidic device with W-shaped electrodes is designed to separate the micro-bio-particles. The microfluidic device efficiently separates the red blood cells (RBCs) and platelets using the dielectrophoresis technique. The separation process has been analysed by using COMSOL Multiphysics software and found that the electrode with the minimum gap of 25 µm acquired optimum results at an applied voltage of 8 V. The proposed device gave a high separation efficiency of 89.5% and a separation purity of 99.63%. The enhanced microfluidic device gave better results compared to other recent works and is exceptionally suitable for separation of micro-bio-particles.

Original languageEnglish
Pages (from-to)526-536
Number of pages11
JournalInternational Journal of Medical Engineering and Informatics
Volume17
Issue number6
DOIs
Publication statusPublished - 2025
Externally publishedYes

Keywords

  • RBCs
  • dielectrophoresis
  • electric field
  • electrodes
  • flow rate
  • force
  • microchannel
  • non-uniform
  • platelets
  • red blood cells
  • separation

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Biomaterials
  • Biomedical Engineering
  • Health Informatics

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