Abstract
Graphene oxide (GO) has been very useful in many applications however little is known about its toxicity in biological applications. Herein, we report the synthesis of GO and its cytotoxicity against four cancer (adherent and suspension) cell lines namely fibroblast histiocytoma (KM-Luc/GFP), breast (FM3A-Luc), ovarian (OV 2944-HM-1) and fibrosarcoma (NFSaY83). The as-synthesized GO is highly dispersible in water with good optical and structural properties. The cytotoxicity evaluation indicated that the as-prepared GO displayed high cell viability against all the four cancer cell lines and its action was very selective at very high concentration (500 µg/mL) with no significant toxicity towards FM3A-Luc and OV 2944-HM-1 at all concentrations.
| Original language | English |
|---|---|
| Article number | 128470 |
| Journal | Materials Letters |
| Volume | 279 |
| DOIs | |
| Publication status | Published - 15 Nov 2020 |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- Cancer cell lines
- Cytotoxicity
- Graphene oxide
- Hummer's method
ASJC Scopus subject areas
- General Materials Science
- Condensed Matter Physics
- Mechanics of Materials
- Mechanical Engineering
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