Cyclopiamines A and B, novel oxindole metabolites of penicillium cyclopium Westling

Roy F. Bond; Jan C.A. Boeyens; Cedric W. Holzapfel; Pieter S. Steyn

doi:10.1039/p19790001751

Cyclopiamines A and B, novel oxindole metabolites of penicillium cyclopium Westling

Roy F. Bond, Jan C.A. Boeyens, Cedric W. Holzapfel, Pieter S. Steyn

Research output: Contribution to journal › Article › peer-review

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Abstract

The isolation of two new oxindole alkaloids, cyclopiamine A and B, from Penicillium cyclopium is described. The chemical and spectral properties of cyclopiamine B are interpreted in terms of the constitution and relative stereochemistry (2a) of the compound as determined by X-ray structure analysis. The enantiomeric relationship between cyclopiamine A(1) and B(2a) at C(22) is established on the basis of chemical studies.

Original language	English
Pages (from-to)	1751-1761
Number of pages	11
Journal	Journal of the Chemical Society, Perkin Transactions 1
DOIs	https://doi.org/10.1039/p19790001751
Publication status	Published - 1979
Externally published	Yes

ASJC Scopus subject areas

General Chemistry

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title = "Cyclopiamines A and B, novel oxindole metabolites of penicillium cyclopium Westling",

abstract = "The isolation of two new oxindole alkaloids, cyclopiamine A and B, from Penicillium cyclopium is described. The chemical and spectral properties of cyclopiamine B are interpreted in terms of the constitution and relative stereochemistry (2a) of the compound as determined by X-ray structure analysis. The enantiomeric relationship between cyclopiamine A(1) and B(2a) at C(22) is established on the basis of chemical studies.",

author = "Bond, {Roy F.} and Boeyens, {Jan C.A.} and Holzapfel, {Cedric W.} and Steyn, {Pieter S.}",

year = "1979",

doi = "10.1039/p19790001751",

language = "English",

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journal = "Journal of the Chemical Society, Perkin Transactions 1",

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T1 - Cyclopiamines A and B, novel oxindole metabolites of penicillium cyclopium Westling

AU - Bond, Roy F.

AU - Boeyens, Jan C.A.

AU - Holzapfel, Cedric W.

AU - Steyn, Pieter S.

PY - 1979

Y1 - 1979

N2 - The isolation of two new oxindole alkaloids, cyclopiamine A and B, from Penicillium cyclopium is described. The chemical and spectral properties of cyclopiamine B are interpreted in terms of the constitution and relative stereochemistry (2a) of the compound as determined by X-ray structure analysis. The enantiomeric relationship between cyclopiamine A(1) and B(2a) at C(22) is established on the basis of chemical studies.

AB - The isolation of two new oxindole alkaloids, cyclopiamine A and B, from Penicillium cyclopium is described. The chemical and spectral properties of cyclopiamine B are interpreted in terms of the constitution and relative stereochemistry (2a) of the compound as determined by X-ray structure analysis. The enantiomeric relationship between cyclopiamine A(1) and B(2a) at C(22) is established on the basis of chemical studies.

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U2 - 10.1039/p19790001751

DO - 10.1039/p19790001751

M3 - Article

AN - SCOPUS:10644287846

SN - 1472-7781

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JO - Journal of the Chemical Society, Perkin Transactions 1

JF - Journal of the Chemical Society, Perkin Transactions 1

ER -

Cyclopiamines A and B, novel oxindole metabolites of penicillium cyclopium Westling

Abstract

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