Conceptual Molecular Communication Solution for Developing Digital Twin to Enable Precision Medicine Implementation

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

4 Citations (Scopus)

Abstract

In this paper, a molecular communication inspired solution to the development of patients' digital twin models to enable the implementation of precision medicine (PM) is proposed. The proposed solution considers the modeling and analysis of the intercellular communication network of body cells as a complementary in silico approach to enable a timely and patient-specific PM procedure. Fundamental submissions that motivate the idea of the proposed model are presented. Further, based on the ideas behind two global projects, the computational whole-cell model and human cell atlas, a graph-theoretic model that is an abstraction of an organism's cell-to-cell network is developed. The graph network can represent the digital twin model of a patient. By characterizing and analyzing the graph network, the application of the digital twin model is explored. Simple illustrative examples and the ensuing graphical results are used to explore the gains of the proposed digital twin modelling approach.

Original languageEnglish
Title of host publication2021 15th International Conference on Signal Processing and Communication Systems, ICSPCS 2021 - Proceedings
EditorsTadeusz A Wysocki, Beata J Wysocki
PublisherInstitute of Electrical and Electronics Engineers Inc.
ISBN (Electronic)9781665436991
DOIs
Publication statusPublished - 2021
Event15th International Conference on Signal Processing and Communication Systems, ICSPCS 2021 - Virtual, Online, Australia
Duration: 13 Dec 202115 Dec 2021

Publication series

Name2021 15th International Conference on Signal Processing and Communication Systems, ICSPCS 2021 - Proceedings

Conference

Conference15th International Conference on Signal Processing and Communication Systems, ICSPCS 2021
Country/TerritoryAustralia
CityVirtual, Online
Period13/12/2115/12/21

Keywords

  • graph-theory
  • human cell atlas
  • molecular communication
  • precision medicine
  • whole-cell model

ASJC Scopus subject areas

  • Artificial Intelligence
  • Signal Processing

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