TY - JOUR
T1 - Comprehensive Study of Silver Nanoparticle Functionalization of Kalzhat Bentonite for Medical Application
AU - Nauryzova, Saule Z.
AU - Kabdrakhmanova, Sana K.
AU - Kabdrakhmanova, Ainur K.
AU - Aryp, Kadiran
AU - Shaimardan, Esbol
AU - Kukhareva, Anastassiya D.
AU - Ibraeva, Zhanar E.
AU - Beisebekov, Madiar M.
AU - Kamil, Ahmed M.
AU - Thomas, Martin George
AU - Thomas, Sabu
N1 - Publisher Copyright:
© 2025 by the authors.
PY - 2025/12
Y1 - 2025/12
N2 - The characterization and biomedical modification of bentonite clays from the Kalzhat deposit (Kzh), which is situated in Kazakhstan’s Zhetysu region, are the main objectives of this work. In order to improve the raw material’s structural qualities, the montmorillonite fraction was enriched, and coarse impurities were eliminated using the Salo method. The presence of meso- and micropores that guarantee high dispersity and specific surface area, as well as the prevalence of montmorillonite and kaolinite, was all confirmed by physicochemical analysis. Particle size measurements indicated finely dispersed structures with a propensity to aggregate, whereas thermal analysis demonstrated resilience under heating. After effective functionalization with silver nanoparticles, a porous hybrid system with improved surface reactivity was produced. These enhancements demonstrate the modified bentonite’s usefulness as a multifunctional carrier for the immobilization and controlled release of pharmaceuticals, with potential uses in drug delivery systems, antimicrobial coatings, and wound-healing materials. The material has potential use in sorption and environmental protection technologies in addition to its biomedical application. Overall, Kzh’s structural and functional performance is greatly improved by the combination of purification and functionalization with silver nanoparticles, highlighting its promise as a useful element in the development of next-generation polymer–composite systems.
AB - The characterization and biomedical modification of bentonite clays from the Kalzhat deposit (Kzh), which is situated in Kazakhstan’s Zhetysu region, are the main objectives of this work. In order to improve the raw material’s structural qualities, the montmorillonite fraction was enriched, and coarse impurities were eliminated using the Salo method. The presence of meso- and micropores that guarantee high dispersity and specific surface area, as well as the prevalence of montmorillonite and kaolinite, was all confirmed by physicochemical analysis. Particle size measurements indicated finely dispersed structures with a propensity to aggregate, whereas thermal analysis demonstrated resilience under heating. After effective functionalization with silver nanoparticles, a porous hybrid system with improved surface reactivity was produced. These enhancements demonstrate the modified bentonite’s usefulness as a multifunctional carrier for the immobilization and controlled release of pharmaceuticals, with potential uses in drug delivery systems, antimicrobial coatings, and wound-healing materials. The material has potential use in sorption and environmental protection technologies in addition to its biomedical application. Overall, Kzh’s structural and functional performance is greatly improved by the combination of purification and functionalization with silver nanoparticles, highlighting its promise as a useful element in the development of next-generation polymer–composite systems.
KW - bentonite
KW - biomedical materials
KW - montmorillonite
KW - silver nanoparticles
KW - surface modification
UR - https://www.scopus.com/pages/publications/105025953817
U2 - 10.3390/jcs9120702
DO - 10.3390/jcs9120702
M3 - Article
AN - SCOPUS:105025953817
SN - 2504-477X
VL - 9
JO - Journal of Composites Science
JF - Journal of Composites Science
IS - 12
M1 - 702
ER -