Comprehensive reviews on adverse health effects of human exposure to endocrine-disrupting chemicals

Hussein Kehinde Okoro, Julius Oluwafunso Ige, Oluyinka Ajibola Iyiola, Sadanand Pandey, Isiaka Ayobamidele Lawal, Caliphs Zvinowanda, Catherine Jane Ngila

Research output: Contribution to journalReview articlepeer-review

22 Citations (Scopus)

Abstract

Endocrine disruption refers to the ability of chemicals or substances at a certain dose to interfere with hormonal systems in the body. This has brought genuine concern globally in recent years. Endocrine disruptive chemicals (EDCs) represent a serious health risk to human and wildlife and have the tendency to impact human health negatively. This review focuses on the health impact of EDCs. There is growing interest from researchers, scientists and standard organization across the globe on the possible health threat posed by endocrine disrupting chemicals (EDCs), which are substances we get exposed to on a daily basis in our environment, food, drinks and consumer products (creams, drugs, addictive, plastics, children toy etc.) that interfere with hormone biosynthesis, action resulting in a deviation from normal homeostatic control or reproduction and metabolism. Moreover, EDCs represent a broad class of molecules such as industrial chemicals and organo-chlorinated pesticides, plasticizers and plastics, fuels, and many more chemicals that are present in the environment or are in extensive use. This article focuses on making suggestions to broaden society knowledge of the health risk of EDCs, including enhancing increased basic and clinical research, invoking the precautionary principle, and advocating involvement of individual and scientific society stakeholders in communicating and implementing changes in public policy and awareness.

Original languageEnglish
Pages (from-to)4623-4636
Number of pages14
JournalFresenius Environmental Bulletin
Volume26
Issue number7
Publication statusPublished - Jul 2017

Keywords

  • DDTs
  • Endocrine disruptive chemicals
  • Endocrine disruptor
  • Health impact
  • PCBs

ASJC Scopus subject areas

  • Environmental Chemistry
  • Waste Management and Disposal
  • Pollution

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