Complex etiology and pathology of mycotoxic nephropathy in South African pigs

Stoycho D. Stoev; Stefan Denev; Mike F. Dutton; Patrick B. Njobeh; Joseph S. Mosonik; Paul A. Steenkamp; Iordan Petkov

doi:10.1007/s12550-009-0038-7

Complex etiology and pathology of mycotoxic nephropathy in South African pigs

Stoycho D. Stoev, Stefan Denev, Mike F. Dutton, Patrick B. Njobeh, Joseph S. Mosonik, Paul A. Steenkamp, Iordan Petkov

Biotechnology and Food Technology

Research output: Contribution to journal › Article › peer-review

41 Citations (Scopus)

Abstract

Spontaneous nephropathy in pigs seen in South Africa was found to have multi-mycotoxic etiology involving several mycotoxins such as ochratoxin A (OTA), penicillic acid (PA) and fumonisin B₁ (FB₁) in addition to a not yet identified mycotoxin. Contamination levels of OTA were comparatively low (67-75 μg/kg) in contrast to high contamination levels of FB₁ (5,289-5,021 μg/kg) and PA (149-251 μg/kg). A heavy contamination with Gibberella fujikuroi var. moniliformis and Penicillium aurantiogriseum complex (mainly P. polonicum) was observed in the fed forages in contrast to the light contamination with Aspergillus ochraceus, P. verrucosum and P. citrinum. The pathomorphological picture of this nephropathy was found to differ from the classical description of mycotoxic porcine nephropathy as originally made in Scandinavia by the extensive vascular changes.

Original language	English
Pages (from-to)	31-46
Number of pages	16
Journal	Mycotoxin Research
Volume	26
Issue number	1
DOIs	https://doi.org/10.1007/s12550-009-0038-7
Publication status	Published - Feb 2010

Keywords

Citrinin
Fumonisin B
Mycotoxic nephropathy
Mycotoxins
Ochratoxin A
Penicillic acid
Pigs

ASJC Scopus subject areas

Biotechnology
Microbiology
Toxicology

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10.1007/s12550-009-0038-7

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title = "Complex etiology and pathology of mycotoxic nephropathy in South African pigs",

abstract = "Spontaneous nephropathy in pigs seen in South Africa was found to have multi-mycotoxic etiology involving several mycotoxins such as ochratoxin A (OTA), penicillic acid (PA) and fumonisin B1 (FB1) in addition to a not yet identified mycotoxin. Contamination levels of OTA were comparatively low (67-75 μg/kg) in contrast to high contamination levels of FB1 (5,289-5,021 μg/kg) and PA (149-251 μg/kg). A heavy contamination with Gibberella fujikuroi var. moniliformis and Penicillium aurantiogriseum complex (mainly P. polonicum) was observed in the fed forages in contrast to the light contamination with Aspergillus ochraceus, P. verrucosum and P. citrinum. The pathomorphological picture of this nephropathy was found to differ from the classical description of mycotoxic porcine nephropathy as originally made in Scandinavia by the extensive vascular changes.",

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AU - Steenkamp, Paul A.

AU - Petkov, Iordan

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Complex etiology and pathology of mycotoxic nephropathy in South African pigs

Abstract

Keywords

ASJC Scopus subject areas

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