TY - JOUR
T1 - Comparative alteration in atherogenic indices and hypocholesteremic effect of palm oil and palm oil mill effluent in normal albino rats
AU - Ajiboye, John A.
AU - Erukainure, Ochuko L.
AU - Lawal, Babatunde A.
AU - Nwachukwu, Viola A.
AU - Tugbobo-Amisu, Adesewa O.
AU - Okafor, Ebelechukwu N.
N1 - Publisher Copyright:
© 2015 The Authors.
PY - 2015
Y1 - 2015
N2 - The comparative hypocholesteremic effect of feeding palm oil and palm oil mill effluent (POME) was investigated in male albino rats. Diets were prepared and designed to contain 50% of energy as carbohydrate, 35% as fat, and 15% as protein. Groups of six rats were each fed one of these diets, while a group was fed pelletized mouse chow which served as the control. Feeding on palm oil and POME led to a significant increase (p < 0.05) in serum total cholesterol, triglyceride, and vLDL. Feeding on POME led to significant increase (p < 0.05) in cholesterol, triglyceride and LDL levels in brain tissues. Increased hepatic LDL level was also observed in POME fed rats. Except for hepatic triglyceride and tissues HDL level, a rather reduced level of the studied lipids was observed in the serum and tissues of palm oil fed rats compared to POME. These results indicate the protective potentials of palm oil against cardiovascular disease, as well as hyperlipidemia that characterize obesity and hypertension; as compared to its effluent.
AB - The comparative hypocholesteremic effect of feeding palm oil and palm oil mill effluent (POME) was investigated in male albino rats. Diets were prepared and designed to contain 50% of energy as carbohydrate, 35% as fat, and 15% as protein. Groups of six rats were each fed one of these diets, while a group was fed pelletized mouse chow which served as the control. Feeding on palm oil and POME led to a significant increase (p < 0.05) in serum total cholesterol, triglyceride, and vLDL. Feeding on POME led to significant increase (p < 0.05) in cholesterol, triglyceride and LDL levels in brain tissues. Increased hepatic LDL level was also observed in POME fed rats. Except for hepatic triglyceride and tissues HDL level, a rather reduced level of the studied lipids was observed in the serum and tissues of palm oil fed rats compared to POME. These results indicate the protective potentials of palm oil against cardiovascular disease, as well as hyperlipidemia that characterize obesity and hypertension; as compared to its effluent.
KW - Atherogenic indices
KW - Hypocholestermia
KW - Palm oil and POME
UR - https://www.scopus.com/pages/publications/84942765873
U2 - 10.1016/j.heliyon.2015.e00010
DO - 10.1016/j.heliyon.2015.e00010
M3 - Article
AN - SCOPUS:84942765873
SN - 2405-8440
VL - 1
JO - Heliyon
JF - Heliyon
IS - 1
M1 - e00010
ER -
