Combination of zeolitic imidazolate framework-67 and magnetic porous porphyrin organic polymer for preconcentration of neonicotinoid insecticides in river water

A nanostructured material composed of zeolitic imidazolate framework-67 and magnetic porous porphyrin organic polymer (ZIF-67@MPPOP) was successfully synthesized and applied for the enrichment of neonicotinoid insecticides in river water. The analytes were detected and quantified using high performance liquid chromatography coupled with diode array detector (HPLC-DAD) and liquid chromatography mass spectrometry (LC-MS). Influential experimental parameters were optimized using response surface methodology based on Box Behnken design. The adsorption capacities were 69.46, 80.53, 85.39 and 90.0 mg g⁻¹ for thiamethoxam, imidacloprid, acetamiprid and clothianidin, respectively. At optimal experimental conditions, low limit of detection (LOD), limit of quantification (LOQ) and linearity were 0.0091–0.04 µg L⁻¹, 0.04–0.13 µg L⁻¹ and (0.04-600 µg L⁻¹), respectively. The relative standard deviation used to evaluate the reproducibility and repeatability of the method was less than 5%. Finally, the method was employed for determination of four neonicotinoid insecticides in river water.