TY - JOUR
T1 - Clinical Profile of Primary Open-angle Glaucoma Patients at an Eye Center in Nigeria
AU - Ezinne, Ngozika E.
AU - Kwarteng, Michael A.
AU - Ekemiri, Kingsley K.
AU - Iroanachi, Victoria I.
AU - Tagoh, Selassie
AU - Ogbonna, Grace
AU - Mashige, Khathutshelo P.
N1 - Publisher Copyright:
© The Author(s). 2023.
PY - 2023/7/1
Y1 - 2023/7/1
N2 - Aim: Globally, one of the leading causes of preventable blindness is primary open-angle glaucoma (POAG). The study assessed the clinical presentations of POAG patients attending an eye center in Abuja, Nigeria. Materials and methods: Records of 188 eyes, collected from 94 patients diagnosed with POAG for a period of 1 year at the eye center, were reviewed. Clinical records, including age, gender, visual acuity (VA), central cornea thickness (CCT), intraocular pressure (IOP), cup-to-disk ratios, and retinal nerve fiber layer (RNFL) thickness of the participants, were extracted and analyzed. Results: The majority of the participants were males (56.4%) and adults (57.4%), most of whom had normal VA (>70% in each eye). Our analysis revealed normal average estimates of RNFL thickness, IOP, and CCT among the participants. Females had thicker RNFL compared to males (p = 0.02). Although CCT decreased with age (r = −0.28, p = 0.005), there was no such link between IOP and CCT (r = 0.09, p = 0.38). Conclusion: Central cornea thickness (CCT), RNFL thickness, and IOP in isolation should not be used as early indicators for POAG; rather, a combination of these and other indices is recommended. Early detection through active screening and treatment in the community for at-risk groups is highly advised.
AB - Aim: Globally, one of the leading causes of preventable blindness is primary open-angle glaucoma (POAG). The study assessed the clinical presentations of POAG patients attending an eye center in Abuja, Nigeria. Materials and methods: Records of 188 eyes, collected from 94 patients diagnosed with POAG for a period of 1 year at the eye center, were reviewed. Clinical records, including age, gender, visual acuity (VA), central cornea thickness (CCT), intraocular pressure (IOP), cup-to-disk ratios, and retinal nerve fiber layer (RNFL) thickness of the participants, were extracted and analyzed. Results: The majority of the participants were males (56.4%) and adults (57.4%), most of whom had normal VA (>70% in each eye). Our analysis revealed normal average estimates of RNFL thickness, IOP, and CCT among the participants. Females had thicker RNFL compared to males (p = 0.02). Although CCT decreased with age (r = −0.28, p = 0.005), there was no such link between IOP and CCT (r = 0.09, p = 0.38). Conclusion: Central cornea thickness (CCT), RNFL thickness, and IOP in isolation should not be used as early indicators for POAG; rather, a combination of these and other indices is recommended. Early detection through active screening and treatment in the community for at-risk groups is highly advised.
KW - Abuja
KW - Central cornea thickness
KW - Intraocular pressure
KW - Nigeria
KW - Primary open-angle glaucoma
KW - Retinal nerve fiber layer thickness
UR - https://www.scopus.com/pages/publications/85174586159
U2 - 10.5005/jp-journals-10078-1413
DO - 10.5005/jp-journals-10078-1413
M3 - Article
AN - SCOPUS:85174586159
SN - 0974-0333
VL - 17
SP - 113
EP - 117
JO - Journal of Current Glaucoma Practice
JF - Journal of Current Glaucoma Practice
IS - 3
ER -