TY - JOUR
T1 - Clinical management of COVID-19
T2 - Experiences of the COVID-19 epidemic from Groote Schuur Hospital, Cape Town, South Africa
AU - Mendelson, M.
AU - Boloko, L.
AU - Boutall, A.
AU - Cairncross, L.
AU - Calligaro, G.
AU - Coccia, C.
AU - Dave, J. A.
AU - de Villiers, M.
AU - Dlamini, S.
AU - Frankenfeld, P.
AU - Gina, P.
AU - Gule, M. V.
AU - Hoare, J.
AU - Hofmeyr, R.
AU - Hsiao, M.
AU - Joubert, I.
AU - Kahn, T.
AU - Krause, R.
AU - Kroopman, A.
AU - Levin, D.
AU - Maughan, D.
AU - Mazondwa, S.
AU - Meintjes, G.
AU - Nordien, R.
AU - Ntusi, N.
AU - Papavarnavas, N.
AU - Peter, J.
AU - Pickard, H.
AU - Raubenheimer, P.
AU - Said-Hartley, Q.
AU - Singh, P.
AU - Wasserman, S.
N1 - Publisher Copyright:
© 2020 South African Medical Association. All rights reserved.
PY - 2020/10
Y1 - 2020/10
N2 - The SARS-CoV-2 pandemic has presented clinicians with an enormous challenge in managing a respiratory virus that is not only capable of causing severe pneumonia and acute respiratory distress syndrome, but also multisystem disease. The extraordinary pace of clinical research, and particularly the surge in adaptive trials of new and repurposed treatments, have provided rapid answers to questions of whether such treatments work, and has resulted in corticosteroids taking centre stage in the management of hospitalised patients requiring oxygen support. Some treatment modalities, such as the role of anticoagulation to prevent and treat potential thromboembolic complications, remain controversial, as does the use of high-level oxygen support, outside of an intensive care unit setting. In this article, we describe the clinical management of COVID-19 patients admitted to Groote Schuur Hospital, a major tertiary level hospital at the epicentre of South Africa’s SARS-CoV-2 epidemic during its first 4 months.
AB - The SARS-CoV-2 pandemic has presented clinicians with an enormous challenge in managing a respiratory virus that is not only capable of causing severe pneumonia and acute respiratory distress syndrome, but also multisystem disease. The extraordinary pace of clinical research, and particularly the surge in adaptive trials of new and repurposed treatments, have provided rapid answers to questions of whether such treatments work, and has resulted in corticosteroids taking centre stage in the management of hospitalised patients requiring oxygen support. Some treatment modalities, such as the role of anticoagulation to prevent and treat potential thromboembolic complications, remain controversial, as does the use of high-level oxygen support, outside of an intensive care unit setting. In this article, we describe the clinical management of COVID-19 patients admitted to Groote Schuur Hospital, a major tertiary level hospital at the epicentre of South Africa’s SARS-CoV-2 epidemic during its first 4 months.
UR - http://www.scopus.com/inward/record.url?scp=85092320850&partnerID=8YFLogxK
U2 - 10.7196/SAMJ.2020.v110i10.15157
DO - 10.7196/SAMJ.2020.v110i10.15157
M3 - Article
C2 - 33205723
AN - SCOPUS:85092320850
SN - 0256-9574
VL - 110
SP - 973
EP - 981
JO - South African Medical Journal
JF - South African Medical Journal
IS - 10
ER -
