Carbohydrates as spiroketal precursors

Cedric W. Holzapfel, Madrie Portwig, D. Bradley G. Williams

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)


The preparation of some chiral spiroketals from carbohydrate precursors is described. The reversibility of the Lewis acid-catalysed ketalisation reaction ensured the dominance of the anomeric effect in determining the stereochemical outcome of the spiroketalisation step. In this way, enantiomerically pure products could be obtained from readily available starting materials.

Original languageEnglish
Pages (from-to)165-167
Number of pages3
JournalSouth African Journal of Chemistry
Issue number4
Publication statusPublished - 1999

ASJC Scopus subject areas

  • General Chemistry


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