Bisphosphorylation of a vic-diol using a phosphite approach: Synthesis of myo-inositol 4,5-bisphosphate

Michael R. Hamblin; Barry V.L. Potter; Roy Gigg

doi:10.1039/C39870000626

Bisphosphorylation of a vic-diol using a phosphite approach: Synthesis of myo-inositol 4,5-bisphosphate

Michael R. Hamblin, Barry V.L. Potter, Roy Gigg

Research output: Contribution to journal › Article › peer-review

28 Citations (Scopus)

Abstract

(±)-myo-Inositol 4,5-bisphosphate was synthesized using a phosphite chemistry approach; bisphosphorylation was confirmed by the observation of the first ⁵J_PP coupling in a bisphosphite triester intermediate.

Original language	English
Pages (from-to)	626-627
Number of pages	2
Journal	Chemical Communications
Issue number	8
DOIs	https://doi.org/10.1039/C39870000626
Publication status	Published - 1987
Externally published	Yes

ASJC Scopus subject areas

Molecular Medicine

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title = "Bisphosphorylation of a vic-diol using a phosphite approach: Synthesis of myo-inositol 4,5-bisphosphate",

abstract = "(±)-myo-Inositol 4,5-bisphosphate was synthesized using a phosphite chemistry approach; bisphosphorylation was confirmed by the observation of the first 5JPP coupling in a bisphosphite triester intermediate.",

author = "Hamblin, {Michael R.} and Potter, {Barry V.L.} and Roy Gigg",

year = "1987",

doi = "10.1039/C39870000626",

language = "English",

pages = "626--627",

journal = "Chemical Communications",

issn = "0022-4936",

publisher = "Royal Society of Chemistry",

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T1 - Bisphosphorylation of a vic-diol using a phosphite approach

T2 - Synthesis of myo-inositol 4,5-bisphosphate

AU - Hamblin, Michael R.

AU - Potter, Barry V.L.

AU - Gigg, Roy

PY - 1987

Y1 - 1987

N2 - (±)-myo-Inositol 4,5-bisphosphate was synthesized using a phosphite chemistry approach; bisphosphorylation was confirmed by the observation of the first 5JPP coupling in a bisphosphite triester intermediate.

AB - (±)-myo-Inositol 4,5-bisphosphate was synthesized using a phosphite chemistry approach; bisphosphorylation was confirmed by the observation of the first 5JPP coupling in a bisphosphite triester intermediate.

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U2 - 10.1039/C39870000626

DO - 10.1039/C39870000626

M3 - Article

AN - SCOPUS:37049079648

SN - 0022-4936

SP - 626

EP - 627

JO - Chemical Communications

JF - Chemical Communications

IS - 8

ER -

Bisphosphorylation of a vic-diol using a phosphite approach: Synthesis of myo-inositol 4,5-bisphosphate

Abstract

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