Biopolymer stimuli-responsive in situ hydrogels, chemistry, and their potential applications in ODDS

Jonathan Tersur Orasugh, Dipankar Chattopadhayay, Suprakas Sinha Ray, Anjan Adhikari

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

Ocular drug delivery (DD) is a challenging field that necessitates innovative solutions to overcome the anatomical and physiological barriers of the eye. In recent years, biopolymer-based stimuli-responsive in situ hydrogels have emerged as a promising approach to enhance the efficacy and patient compliance of ocular DD. This chapter provides a comprehensive overview of the chemistry and potential applications of these innovative hydrogels in ocular DD systems (ODDS). This chapter offers a comprehensive insight into the chemistry and versatile applications of biopolymer-based stimuli-responsive in situ hydrogels in the realm of ODDS. It underscores the potential of these innovative DD platforms to revolutionize the treatment of ocular diseases and improve patient outcomes.

Original languageEnglish
Title of host publicationStimuli-Responsive Hydrogels for Ophthalmic Drug Delivery
PublisherElsevier
Pages213-238
Number of pages26
ISBN (Electronic)9780323991568
ISBN (Print)9780323993593
DOIs
Publication statusPublished - 1 Jan 2024

Keywords

  • Bioavailability
  • Biopolymers
  • Chemistry
  • Drug delivery systems
  • In-situ hydrogels
  • Stimuli responsiveness
  • Sustained drug release

ASJC Scopus subject areas

  • General Engineering
  • General Materials Science

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