Biopolymer encapsulation of CdTe quantum dot for in-vitro controlled drug delivery release of 6-mercaptopurine

Sundarrajan Parani, Baddireddi Subhadra Lakshmi, Kannaiyan Pandian

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

4 Citations (Scopus)

Abstract

Alginate biopolymer stabilized CdTe quantum dot (QD) was prepared and it was encapsulated with folic acid conjugated chitosan for controlled drug delivery of anticancer drug 6-mercaptopurine (6-MP). In addition to alginate, chitosan enhances the stability of QD. Also, in addition to chitosan, alginate binds to the drug leading to enhance the loading efficiency of the resulting drug carrier. The drug release profile of the carrier was investigated by in-vitro. The present study has shown that this drug carrier is feasible for drug delivery and will be important beneficiary for cancer therapy.

Original languageEnglish
Title of host publicationRecent Trends in Advanced Materials
Pages258-262
Number of pages5
DOIs
Publication statusPublished - 2012
Externally publishedYes
EventInternational Conference on Recent Trends in Advanced Materials, ICRAM 2012 - Vellore, TN, India
Duration: 20 Feb 201222 Feb 2012

Publication series

NameAdvanced Materials Research
Volume584
ISSN (Print)1022-6680

Conference

ConferenceInternational Conference on Recent Trends in Advanced Materials, ICRAM 2012
Country/TerritoryIndia
CityVellore, TN
Period20/02/1222/02/12

Keywords

  • 6-mercaptopurine
  • Alginate
  • Cancer
  • Chitosan
  • Drug delivery
  • Quantum dots

ASJC Scopus subject areas

  • General Engineering

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