Abstract
Biopolymer-based composites have received attention for their worth in medical fields and their usage is increasing considerably owing to their optimal mechanical properties, low immunogenicity, ease of availability form natural sources, and high biocompatibility and biodegradation. Most biopolymers used for medical applications are derived from proteins and polysaccharides, which includes both terrestrial and marine based polysaccharides. Various methods are utilized to produce biopolymer-based composites for medical applications, such as casting/solvent evaporation, freeze-drying, electrospinning, three-dimensional (3D) printing, deposition-precipitation, nanoprecipitation, film casting, forcespinning and gelation methods. In this article, we focus on the types of biopolymers derived from natural sources, fabrication methodology, therapeutic application, recent advances of different proteins and polysaccharides available to synthesize biopolymer-based composites, and their functional role in the field of tissue engineering, medical implants, drug delivery systems, and wound healing. Moreover, this article briefly provides an overview of clinical applications and major global clinical trial status of biopolymers in medical applications.
Original language | English |
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Title of host publication | Encyclopedia of Renewable and Sustainable Materials |
Subtitle of host publication | Volume 1-5 |
Publisher | Elsevier |
Pages | 20-28 |
Number of pages | 9 |
Volume | 1-5 |
ISBN (Electronic) | 9780128131961 |
ISBN (Print) | 9780128131954 |
DOIs | |
Publication status | Published - 1 Jan 2020 |
Keywords
- Biopolymer
- Chitosan
- Collagen
- Composites
- Hyaluronic acid
- Medical applications
- Polysaccharides
- Proteins
- Starch
- Tissue engineering
- Wound healing
ASJC Scopus subject areas
- General Arts and Humanities