Abstract
Typhoid fever is a systemic infection caused by Salmonella Typhi and occurs predominantly in association with poor sanitation and lack of clean drinking water. Despite recent progress in water and sanitation coverage, the disease remains a substantial public health problem in many developing countries. A mathematical model for the spread of typhoid has been formulated using non linear ordinary differential equations. The model includes a special treatment function to assess the effects of limited treatment resources on the spread of typhoid. It is shown that the model has multiple equilibria and using the center manifold theory, the model exhibits the phenomenon of backward bifurcation whose implications are discussed. The results suggest the need for comprehensive and accessible treatment facilities to curtail typhoid infection.
Original language | English |
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Pages (from-to) | 647-670 |
Number of pages | 24 |
Journal | Journal of Mathematical Biology |
Volume | 77 |
Issue number | 3 |
DOIs | |
Publication status | Published - 1 Sept 2018 |
Externally published | Yes |
Keywords
- Reproduction number
- Treatment
- Treatment function
- Typhoid
ASJC Scopus subject areas
- Modeling and Simulation
- Agricultural and Biological Sciences (miscellaneous)
- Applied Mathematics