Application of Biaryl Phosphacycles in Palladium-Catalysed Suzuki-Miyaura Cross-Coupling Reactions of Aryl Chlorides

Jairus L. Lamola, Paseka T. Moshapo, Cedric W. Holzapfel, Munaka Christopher Maumela

Research output: Contribution to journalArticlepeer-review

Abstract

The use of Pd-catalysts based on biaryl phosphacycles allowed facile Suzuki-Miyaura couplings of a wide range of deactivated, sterically hindered, and heteroaryl chloride substrates with aryl boronic acids. Notably, the strongly electron-deficient and sufficiently hindered biaryl phosphacycle ligand 7 consistently demonstrated effective performance.

Original languageEnglish
Article numbere202400068
JournalEuropean Journal of Inorganic Chemistry
Volume27
Issue number17
DOIs
Publication statusPublished - 12 Jun 2024

Keywords

  • aryl chlorides
  • biaryl
  • cross-coupling
  • electronic
  • phosphines
  • steric

ASJC Scopus subject areas

  • Inorganic Chemistry

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