Application of aminocarbonylation in the synthesis of a lavendamycin synthon

Cedric W. Holzapfel; Wilhelmina Marais

doi:10.3184/030823402103170349

Application of aminocarbonylation in the synthesis of a lavendamycin synthon

Cedric W. Holzapfel
, Wilhelmina Marais

Chemical Sciences

University of Johannesburg

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

An efficient route to a key intermediate in the synthesis of lavendamycin from a suitably substituted 2-chloroquino-line derivative via aminocarbonylation with tryptophan methyl ester as nucleophile, is reported.

Original language	English
Pages (from-to)	22-24
Number of pages	3
Journal	Journal of Chemical Research - Part S
Issue number	1
DOIs	https://doi.org/10.3184/030823402103170349
Publication status	Published - 2002

Keywords

Aminocarbonylation
Lavendamycin
Palladium catalysis
Quinolines
Tryptophan

ASJC Scopus subject areas

General Chemistry

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10.3184/030823402103170349

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title = "Application of aminocarbonylation in the synthesis of a lavendamycin synthon",

abstract = "An efficient route to a key intermediate in the synthesis of lavendamycin from a suitably substituted 2-chloroquino-line derivative via aminocarbonylation with tryptophan methyl ester as nucleophile, is reported.",

keywords = "Aminocarbonylation, Lavendamycin, Palladium catalysis, Quinolines, Tryptophan",

author = "Holzapfel, \{Cedric W.\} and Wilhelmina Marais",

year = "2002",

doi = "10.3184/030823402103170349",

language = "English",

pages = "22--24",

journal = "Journal of Chemical Research - Part S",

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T1 - Application of aminocarbonylation in the synthesis of a lavendamycin synthon

AU - Holzapfel, Cedric W.

AU - Marais, Wilhelmina

PY - 2002

Y1 - 2002

N2 - An efficient route to a key intermediate in the synthesis of lavendamycin from a suitably substituted 2-chloroquino-line derivative via aminocarbonylation with tryptophan methyl ester as nucleophile, is reported.

AB - An efficient route to a key intermediate in the synthesis of lavendamycin from a suitably substituted 2-chloroquino-line derivative via aminocarbonylation with tryptophan methyl ester as nucleophile, is reported.

KW - Aminocarbonylation

KW - Lavendamycin

KW - Palladium catalysis

KW - Quinolines

KW - Tryptophan

UR - https://www.scopus.com/pages/publications/0036123282

U2 - 10.3184/030823402103170349

DO - 10.3184/030823402103170349

M3 - Article

AN - SCOPUS:0036123282

SN - 0308-2342

SP - 22

EP - 24

JO - Journal of Chemical Research - Part S

JF - Journal of Chemical Research - Part S

IS - 1

ER -

Application of aminocarbonylation in the synthesis of a lavendamycin synthon

Abstract

Keywords

ASJC Scopus subject areas

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