Antiobesity effect of healthy food crops and functional foods: A systematic review of their mechanisms

Beatrice Mofoluwaso Oladimeji, Oluwafemi Ayodeji Adebo

Research output: Contribution to journalReview articlepeer-review


Diet is a modifiable risk factor in the prevention and management of obesity, and various foods have the potential to aid in obesity management by modulating different pathways involved in the disease's pathology. We performed a systematic review of literature, using CINAHL, PubMed, and Google Scholar, focusing on the antiobesity potential of foods crops and functional food products, and their mechanisms of action and clinical evidence. Sixty-four articles were identified, of which 41 investigated food crops, while 23 investigated functional products. Food crops, such as cereals, vegetables, fruits, mushrooms, seaweeds, legumes, herbs, spices, and cocoa seeds, have antiobesity effects through mechanisms such as altering the metabolism of glucolipids by inhibiting enzymes like α-amylase and α-glucosidase, stimulating the bioenergetics of thermogenic fat, modulating gut microbiota, and inhibiting lipogenesis and storage. In addition, developed functional teas, beverages, and yoghurt have antiobesity effects through similar or different mechanisms, such as enhancing energy expenditure and satiety, suppressing adipogenesis and lipolysis, improving glucose and lipid metabolism, and altering hormonal secretion. This review reemphasized the significance of food in the control of obesity, and highlights the distinct methods these explored foods exert their antiobesity effects. In conclusion, foods are safe and effective means of combating obesity without the side effects of conventional drugs, which can help inform dietary choices, assist professionals in providing more accurate advice, and also lead to better understanding of food and its effect on overall health of the public. This approach will eradicate global diseases, especially if more underutilized and indigenous food crops are extensively researched.

Original languageEnglish
Pages (from-to)1380-1398
Number of pages19
JournalFood Science and Nutrition
Issue number3
Publication statusPublished - Mar 2024


  • food crops
  • functional foods
  • mechanisms of action
  • obesity management

ASJC Scopus subject areas

  • Food Science


Dive into the research topics of 'Antiobesity effect of healthy food crops and functional foods: A systematic review of their mechanisms'. Together they form a unique fingerprint.

Cite this