An Electrochemical Aptamer Biosensor for Bisphenol A on a Carbon Nanofibre-silver Nanoparticle Immobilisation Platform

Tebogo R. Tsekeli, Luthando Tshwenya, Tsholofelo I. Sebokolodi, Thabile Ndlovu, Omotayo A. Arotiba

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)

Abstract

A nanocomposite platform of silver nanoparticles and carbon nanofibres (AgCNFs) was used to immobilise a bisphenol A specific 63-mer ssDNA aptamer to form a biosensor. The fabrication process of the biosensor was studied with electrochemical impedance spectroscopy and cyclic voltammetry in the presence of [Fe(CN)6]3−/4− as redox probe. The biosensor detected bisphenol A in a linear range of 0.1–10 nM, with a limit of detection of 0.39 nM using square wave voltammetry (SWV). The biosensor exhibited good selectivity in the presence of interfering species at 100-fold concentrations and was used to detect BPA in real water sample.

Original languageEnglish
Pages (from-to)2053-2061
Number of pages9
JournalElectroanalysis
Volume33
Issue number9
DOIs
Publication statusPublished - Sept 2021

Keywords

  • Bisphenol A
  • aptamer
  • biosensor
  • carbon nanofibres
  • immobilisation platform
  • silver nanoparticles

ASJC Scopus subject areas

  • Analytical Chemistry
  • Electrochemistry

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