Adult antiretroviral therapy guidelines 2014

G. Meintjes, J. Black, F. Conradie, V. Cox, S. Dlamini, J. Fabian, G. Maartens, T. Manzini, M. Mathe, C. Menezes, M. Moorhouse, Y. Moosa, J. Nash, C. Orrell, Y. Pakade, F. Venter, D. Wilson, African HIV Clinicians Society Southern African HIV Clinicians Society

Research output: Contribution to journalArticlepeer-review

31 Citations (Scopus)

Abstract

These guidelines are intended as an update to those published in the Southern African Journal of HIV Medicine in 2012. Since the release of the previous guidelines, the scale-up of antiretroviral therapy (ART) in southern Africa has continued. Cohort studies from the region show excellent clinical outcomes; however, ART is still being initiated late (in advanced disease) in some patients, resulting in relatively high early mortality rates. New data on antiretroviral drugs have become available. Although currently few, there are patients in the region who are failing protease-inhibitor-based second-line regimens. To address this, guidelines on third-line therapy have been expanded.

Original languageEnglish
Pages (from-to)121-143
Number of pages23
JournalSouthern African Journal of HIV Medicine
Volume15
Issue number4
DOIs
Publication statusPublished - 1 Dec 2014

ASJC Scopus subject areas

  • Infectious Diseases

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