TY - JOUR
T1 - Adult antiretroviral therapy guidelines 2014
AU - Meintjes, G.
AU - Black, J.
AU - Conradie, F.
AU - Cox, V.
AU - Dlamini, S.
AU - Fabian, J.
AU - Maartens, G.
AU - Manzini, T.
AU - Mathe, M.
AU - Menezes, C.
AU - Moorhouse, M.
AU - Moosa, Y.
AU - Nash, J.
AU - Orrell, C.
AU - Pakade, Y.
AU - Venter, F.
AU - Wilson, D.
AU - Southern African HIV Clinicians Society, African HIV Clinicians Society
PY - 2014/12/1
Y1 - 2014/12/1
N2 - These guidelines are intended as an update to those published in the Southern African Journal of HIV Medicine in 2012. Since the release of the previous guidelines, the scale-up of antiretroviral therapy (ART) in southern Africa has continued. Cohort studies from the region show excellent clinical outcomes; however, ART is still being initiated late (in advanced disease) in some patients, resulting in relatively high early mortality rates. New data on antiretroviral drugs have become available. Although currently few, there are patients in the region who are failing protease-inhibitor-based second-line regimens. To address this, guidelines on third-line therapy have been expanded.
AB - These guidelines are intended as an update to those published in the Southern African Journal of HIV Medicine in 2012. Since the release of the previous guidelines, the scale-up of antiretroviral therapy (ART) in southern Africa has continued. Cohort studies from the region show excellent clinical outcomes; however, ART is still being initiated late (in advanced disease) in some patients, resulting in relatively high early mortality rates. New data on antiretroviral drugs have become available. Although currently few, there are patients in the region who are failing protease-inhibitor-based second-line regimens. To address this, guidelines on third-line therapy have been expanded.
UR - http://www.scopus.com/inward/record.url?scp=84921817100&partnerID=8YFLogxK
U2 - 10.7196/SAJHIVMED.1130
DO - 10.7196/SAJHIVMED.1130
M3 - Article
AN - SCOPUS:84921817100
SN - 1608-9693
VL - 15
SP - 121
EP - 143
JO - Southern African Journal of HIV Medicine
JF - Southern African Journal of HIV Medicine
IS - 4
ER -