Acute and impaired wound healing: Pathophysiology and current methods for drug delivery, part 1: Normal and chronic wounds: Biology, causes, and approaches to care

Tatiana N. Demidova-Rice, Michael R. Hamblin, Ira M. Herman

Research output: Contribution to journalReview articlepeer-review

507 Citations (Scopus)

Abstract

This is the first installment of 2 articles that discuss the biology and pathophysiology of wound healing, review the role that growth factors play in this process, and describe current ways of growth factor delivery into the wound bed. Part 1 discusses the latest advances in clinicians' understanding of the control points that regulate wound healing. Importantly, biological similarities and differences between acute and chronic wounds are considered, including the signaling pathways that initiate cellular and tissue responses after injury, which may be impeded during chronic wound healing.

Original languageEnglish
Pages (from-to)304-314
Number of pages11
JournalAdvances in Skin and Wound Care
Volume25
Issue number7
DOIs
Publication statusPublished - Jul 2012
Externally publishedYes

Keywords

  • Acute wound healing
  • Drug delivery and wounds
  • Wound care strategies

ASJC Scopus subject areas

  • Dermatology
  • Advanced and Specialized Nursing

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