A novel one-pot route for the synthesis of water-soluble cadmium selenide nanoparticles

S. O. Oluwafemi, N. Revaprasadu, A. J. Ramirez

Research output: Contribution to journalArticlepeer-review

59 Citations (Scopus)


A novel, facile one-pot synthetic route to highly water dispersible and potentially biocompatible CdSe nanoparticles is reported. The monodispersed CdSe particles are passivated by cysteine, with water being the solvent. This route involves the reaction of selenium powder with sodium borohydride to produce selenide ions, followed by the addition of a cadmium salt and l-cysteine ethyl ester hydrochloride. The nanoparticles formed show quantum confinement fluorescing in the blue region. Fourier transform infrared spectroscopy study shows that CdSe nanoparticles are capped through mercapto group of the amino acid cysteine whilst its free amino and carboxylate groups make it amenable to bioconjugation establishing the possibility of using these as fluorescent biomarkers. High-resolution transmission electron spectroscopy images of these materials show well-defined, crystalline nanosized particles. Energy dispersive spectroscopy spectra confirm the presence of the corresponding elements.

Original languageEnglish
Pages (from-to)3230-3234
Number of pages5
JournalJournal of Crystal Growth
Issue number13
Publication statusPublished - 15 Jun 2008
Externally publishedYes


  • A1. Biomaterials
  • A1. Nanomaterials
  • A1. Surface structure
  • B1. Cadmium compounds
  • B2. Semiconducting II-VI materials
  • B3. Light emitting diodes

ASJC Scopus subject areas

  • Condensed Matter Physics
  • Inorganic Chemistry
  • Materials Chemistry


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