A new facile synthesis of a thromboxane B2 precursor

Jozua F. Booysen; Cedric W. Holzapfel

doi:10.1080/00397919508011758

A new facile synthesis of a thromboxane B₂ precursor

Jozua F. Booysen, Cedric W. Holzapfel

Chemical Sciences

University of Johannesburg

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

A short, stereocontrolled synthesis of a key intermediate in the synthesis of thromboxane B₂ is described. The approach is based on the use of N, N-diethyl(phenylsulfonyl)acetamide as nucleophile in a palladium-catalysed nucleophilic substitution reaction.

Original language	English
Pages (from-to)	1461-1472
Number of pages	12
Journal	Synthetic Communications
Volume	25
Issue number	10
DOIs	https://doi.org/10.1080/00397919508011758
Publication status	Published - 1 May 1995

ASJC Scopus subject areas

Organic Chemistry

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10.1080/00397919508011758

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title = "A new facile synthesis of a thromboxane B2 precursor",

abstract = "A short, stereocontrolled synthesis of a key intermediate in the synthesis of thromboxane B2 is described. The approach is based on the use of N, N-diethyl(phenylsulfonyl)acetamide as nucleophile in a palladium-catalysed nucleophilic substitution reaction.",

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AU - Holzapfel, Cedric W.

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N2 - A short, stereocontrolled synthesis of a key intermediate in the synthesis of thromboxane B2 is described. The approach is based on the use of N, N-diethyl(phenylsulfonyl)acetamide as nucleophile in a palladium-catalysed nucleophilic substitution reaction.

AB - A short, stereocontrolled synthesis of a key intermediate in the synthesis of thromboxane B2 is described. The approach is based on the use of N, N-diethyl(phenylsulfonyl)acetamide as nucleophile in a palladium-catalysed nucleophilic substitution reaction.

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DO - 10.1080/00397919508011758

M3 - Article

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JO - Synthetic Communications

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IS - 10

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A new facile synthesis of a thromboxane B₂ precursor

Abstract

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