Abstract
Reusable, immobilized AlCl3 on γ-Al2O3 is generated by the reaction of AlCl3 on activated γ-Al2O3 of 58 A˚ at 600°C. This is an efficient, catalytic, safe and environmentally acceptable catalyst for the synthesis of a series of α-aminonitriles utilizing Strecker's process by the reaction of carbonyl compounds, amines and trimethylsilyl cyanide (TMSCN) with excellent yields at ambient temperature. The catalyst can be easily recycled and has been reused for thirteen runs without losing its activity.
Original language | English |
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Pages (from-to) | 110-116 |
Number of pages | 7 |
Journal | Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry |
Volume | 54B |
Issue number | 1 |
Publication status | Published - 1 Jan 2015 |
Keywords
- Immobilized alcl on γ-alo
- Reusable catalyst
- Strecker's reaction
- α-aminonitriles
ASJC Scopus subject areas
- Pharmacology, Toxicology and Pharmaceutics (all)
- Organic Chemistry