A case study of monkeypox disease in the United States using mathematical modeling with real data

Pushpendra Kumar, M. Vellappandi, Zareen A. Khan, Sivalingam S M, Anthony Kaziboni, V. Govindaraj

Research output: Contribution to journalArticlepeer-review

21 Citations (Scopus)

Abstract

In this article, we propose the mathematical modeling of monkeypox, a viral zoonotic disease, to study its near outbreaks in the United States. We use integer and fractional derivatives to simulate the transmission model dynamics effectively. The model parameter values are estimated using the Levenberg–Marquardt algorithm with the lsqcurvefit function in MATLAB. We derive the numerical solution of the integer-order model by using a neural network approach. For solving the fractional-order model, we use the finite-difference predictor–corrector method in the sense of the Caputo derivative. We perform several graphical simulations of future disease outbreaks. Implementing the Caputo fractional derivatives is motivated by its nonlocal nature, which includes memory effects in the model. The new data simulation and various solution approaches are the novelty of this research. This work aims to explore the transmission pattern and duration of a monkeypox outbreak in the United States.

Original languageEnglish
Pages (from-to)444-465
Number of pages22
JournalMathematics and Computers in Simulation
Volume213
DOIs
Publication statusPublished - Nov 2023

Keywords

  • Data-fitting
  • Fractional derivatives
  • Mathematical modeling
  • Monkeypox disease
  • Neural network

ASJC Scopus subject areas

  • Theoretical Computer Science
  • General Computer Science
  • Numerical Analysis
  • Modeling and Simulation
  • Applied Mathematics

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