Mpho Choene

Phone+27 11 559 2497
Emailmchoeneuj.acza
Websitehttps://www.uj.ac.za/dr-mpho-choene

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Research activity per year

Research Interests

The identification of South African medicinal plants in the quest to developing novel cancer therapeutics. Natural products have been playing a significant role in drug discovery as a source of potential cytotoxic agents. My research involves the identification, isolation and characterization of bioactive compounds from natural compounds and the elucidation of their anticancer mechanism.

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

SDG 3 Good Health and Well-being

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Dive into the research topics where Mpho Choene is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

1 Similar Profiles

16 Article
2 Review article
1 Comment/debate

Evaluation of Leptospermum petersonii methanol and ethyl acetate crude extracts for antimetastatic and apoptotic effects against pancreatic and prostate cancer cells
Matlou, M., Choene, M. & Motadi, L., Dec 2025, In: Journal of Applied Pharmaceutical Science. 15, 12, p. 117-133 17 p.
Research output: Contribution to journal › Article › peer-review

Open Access
1 Citation (Scopus)
Hybrid Molecules Containing Methotrexate, Vitamin D, and Platinum Derivatives: Synthesis, Characterization, In Vitro Cytotoxicity, In Silico ADME Docking, Molecular Docking and Dynamics
Mbese, Z., Choene, M., Morifi, E., Nwamadi, M., Adeyemi, S., Kolawole Oyebamiji, A., Adeyinka, A. S., George, B. & Aderibigbe, B. A., Jan 2025, In: Chemistry and Biodiversity. 22, 1, e202400373.
Research output: Contribution to journal › Article › peer-review

Open Access
4 Citations (Scopus)
Mapping the Helichrysum metabolome: uncovering species-specific chemistry through an AI-guided LC-MS/MS workflow
Lephatsi, M. M., Choene, M. S., Kappo, A. P., Madala, N. E. & Tugizimana, F., 1 Nov 2025, In: Molecular Omics. 21, 6, p. 747-759 13 p.
Research output: Contribution to journal › Article › peer-review

Open Access
Molecular mechanism of angiogenesis in colorectal cancer
Raphela-Choma, P. P., Choene, M. S. & Motadi, L. R., Jun 2025, In: Gene Reports. 39, 102163.
Research output: Contribution to journal › Review article › peer-review

Open Access
6 Citations (Scopus)
Retraction Note: Validation of the antiproliferative effects of Euphorbia tirucalli extracts in breast cancer cell lines (Molecular Biology, (2016), 50, 1, (98-110), 10.1134/S0026893316010040)
Choene, M. & Motadi, L., Dec 2025, In: Molecular Biology. 59, Suppl 2, p. S209
Research output: Contribution to journal › Comment/debate

Open Access

Findings from University of Johannesburg in the Area of Science Reported (Mapping the Helichrysum metabolome: uncovering species-specific chemistry through an AI-guided LC-MS/MS workflow)
Kappo, A., Choene, M. & Tugizimana, F.
26/11/25
1 item of Media coverage
Press/Media
Research Results from University of Johannesburg Update Knowledge of Melanoma [Evaluation of Anti-Cancer, Pro-Apoptotic, and Anti-Metastatic Effects of Synthetic Analogue Compound 2-Imino-7-Methoxy-4-(4-fluorophenyl)-2H-1,3-Thiazino [3,2-a] ...]
Motadi, L., Ndou, M., Choene, M., Simelane, M., Ndinteh, D. & Mmutlane, E.
26/02/25
1 item of Media coverage
Press/Media
Findings from University of Johannesburg Advance Knowledge in Xenografts (Antitumor effect of Iso-mukaadial acetate on MCF-7 breast cancer mice xenograft model)
Motadi, L., Simelane, M. & Choene, M.
27/06/24
1 item of Media coverage
Press/Media
Microbiology Society: UJ Researchers Discover New Bacterial Species With Healthcare Potential in South African Medicinal Plant
Serepa-Dlamini, M., Choene, M. & Motadi, L.
15/11/23
1 item of Media coverage
Press/Media

Dr Mpho Choene

Personal profile

Research Interests

Expertise related to UN Sustainable Development Goals

Fingerprint

Collaborations and top research areas from the last five years

Dive into details

Evaluation of Leptospermum petersonii methanol and ethyl acetate crude extracts for antimetastatic and apoptotic effects against pancreatic and prostate cancer cells

Hybrid Molecules Containing Methotrexate, Vitamin D, and Platinum Derivatives: Synthesis, Characterization, In Vitro Cytotoxicity, In Silico ADME Docking, Molecular Docking and Dynamics

Mapping the Helichrysum metabolome: uncovering species-specific chemistry through an AI-guided LC-MS/MS workflow

Molecular mechanism of angiogenesis in colorectal cancer

Retraction Note: Validation of the antiproliferative effects of Euphorbia tirucalli extracts in breast cancer cell lines (Molecular Biology, (2016), 50, 1, (98-110), 10.1134/S0026893316010040)

Findings from University of Johannesburg in the Area of Science Reported (Mapping the Helichrysum metabolome: uncovering species-specific chemistry through an AI-guided LC-MS/MS workflow)

Research Results from University of Johannesburg Update Knowledge of Melanoma [Evaluation of Anti-Cancer, Pro-Apoptotic, and Anti-Metastatic Effects of Synthetic Analogue Compound 2-Imino-7-Methoxy-4-(4-fluorophenyl)-2H-1,3-Thiazino [3,2-a] ...]

Findings from University of Johannesburg Advance Knowledge in Xenografts (Antitumor effect of Iso-mukaadial acetate on MCF-7 breast cancer mice xenograft model)

Microbiology Society: UJ Researchers Discover New Bacterial Species With Healthcare Potential in South African Medicinal Plant

Dr Mpho Choene

Personal profile

Research Interests

Expertise related to UN Sustainable Development Goals

Fingerprint

Collaborations and top research areas from the last five years

Research output

Press/Media