Research output per year
Research output per year
Personal profile
Research Interests
The identification of South African medicinal plants in the quest to developing novel cancer therapeutics. Natural products have been playing a significant role in drug discovery as a source of potential cytotoxic agents. My research involves the identification, isolation and characterization of bioactive compounds from natural compounds and the elucidation of their anticancer mechanism.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Hybrid Molecules Containing Methotrexate, Vitamin D, and Platinum Derivatives: Synthesis, Characterization, In Vitro Cytotoxicity, In Silico ADME Docking, Molecular Docking and Dynamics
Mbese, Z., Choene, M., Morifi, E., Nwamadi, M., Adeyemi, S., Kolawole Oyebamiji, A., Adeyinka, A. S., George, B. & Aderibigbe, B. A., Jan 2025, In: Chemistry and Biodiversity. 22, 1, e202400373.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
Molecular mechanism of angiogenesis in colorectal cancer
Raphela-Choma, P. P., Choene, M. S. & Motadi, L. R., Jun 2025, In: Gene Reports. 39, 102163.Research output: Contribution to journal › Review article › peer-review
Open Access -
Anticancer Activity of Iso - Mukaadial Acetate on Pancreatic and Colon Cancer Cells
Raphela-Choma, P., Motadi, L., Simelane, M. & Choene, M., 2024, In: Reports of Biochemistry and Molecular Biology. 12, 4, p. 586-595 10 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
Antitumor effect of Iso-mukaadial acetate on MCF-7 breast cancer mice xenograft model
Raphela-Choma, P. P., Lukhwareni, R., Simelane, M. B. C., Motadi, L. R. & Choene, M. S., Dec 2024, In: Scientific Reports. 14, 1, 13744.Research output: Contribution to journal › Article › peer-review
Open Access2 Citations (Scopus) -
Charting the Cannabis plant chemical space with computational metabolomics
Myoli, A., Choene, M., Kappo, A. P., Madala, N. E., van der Hooft, J. J. J. & Tugizimana, F., Jun 2024, In: Metabolomics. 20, 3, 62.Research output: Contribution to journal › Article › peer-review
Open Access
Press/Media
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Research Results from University of Johannesburg Update Knowledge of Melanoma [Evaluation of Anti-Cancer, Pro-Apoptotic, and Anti-Metastatic Effects of Synthetic Analogue Compound 2-Imino-7-Methoxy-4-(4-fluorophenyl)-2H-1,3-Thiazino [3,2-a] ...]
Motadi, L., Ndou, M. & Choene, M.
26/02/25
1 item of Media coverage
Press/Media
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Microbiology Society: UJ Researchers Discover New Bacterial Species With Healthcare Potential in South African Medicinal Plant
Serepa-Dlamini, M. & Choene, M.
15/11/23
1 item of Media coverage
Press/Media